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Conservation status of Sun bear (Helarctos malayanus) in Nagaland State, North-East India
Janmejay Sethy,N.P.S. Chauhan
Asian Journal of Conservation Biology , 2012,
Abstract: We carried out survey in a total 16 villages locating in and around the different protected areas in Nagaland. Out of 265 respondent 69 (28.2%) respondents confirmed the presence of sun bear by direct sighting and indirect evidences in 2 PAs of Nagaland. Overall status of sun bear was found to be low and rare in and around Pas. In the Nagaland states, human population is constantly on the increase and as a result, there are increasing biotic pressure on protected areas and reserve forests. The potential tropical rainforest habitats of sun bear should be well protected and management action for improvement these habitats should be taken up on priority. Livestock grazing should be restricted in forest areas. Presence of sun bears has been confirmed in the Itanki and Fakim National Parks of Nagaland, but it showed patchy distribution. Both direct and indirect evidences (scats, claw marks and foot prints) of sun bears were observed by inhabitants of these areas. Sun bears were reported to be sighted and indirect evidences were seen by inhabitants of villages.Public education and awareness programmes towards conservation and natural history of sun bear must be initiated by the forest department. Study on ecology and management of sun bear is also very necessary for formulation of action plan for mitigation of human-sun bear conflict and long term conservation of the species.
Comparison of different Hepatitis B guidelines
Sethy Pradeepta,Goenka Mahesh
Hepatitis B Annual , 2009,
Abstract: Hepatitis B is a global healthcare problem. An estimated one third of the global population have been infected with the hepatitis B virus (HBV). Various guidelines have been proposed for management of chronic hepatitis B. These guidelines have similarities and differences and are changed from time to time. Here, we have reviewed the management guidelines of chronic hepatitis B published after 2007 and highlighted the similarities and differences between their different recommendations.
DISTANCE EDUCATION IN THE AGE OF GLOBALIZATION: An Overwhelming Desire towards Blended Learning
Satya Sundar SETHY
The Turkish Online Journal of Distance Education , 2008,
Abstract: ABSTRACT The aim of this paper is to discuss the nature and status of distance education in the age of globalization, i.e. how best it fits for the present educational scenario. In this connection, we will discuss how Blended Learning (hence after, BL) is one among the other learning strategies mostly helpful for the learners. Keeping this view in mind, this paper is divided into three sections. The first section aims to discuss the nature of distance education in the age of globalization. The second section devotes a discussion on why we need blended learning in ODL system and in which way it plays a vital role for maximizing the benefit of the learners, tutors, and the institutions. The third section explains the pros and cons of blended learning to evaluate how successfully it can be implemented in the ODL system. The paper concludes with an established view that blended learning is a globalized approach to the distance education.
COGNITIVE SKILLS: A Modest Way of Learning through Technology
Satya Sundar SETHY
The Turkish Online Journal of Distance Education , 2012,
Abstract: Learning is an ever-present phenomenon. It takes place irrespective of time and place. It engages learners in their interested topic/content. Learning absorbs many skills, such as; reading skills, writing skills, technological skills, emotional skills, behavioral skills, cognitive skills, and language skills. Out of all these, cognitive skills play significant role for apprehending a concept and comprehending a discussion. In the context of distance education (DE), learning never restrains to print medium only, it has extended to the various technological media with abundant possibilities for multiple variations of online and web instructions. This article discusses how cognitive skills assist learners in their learning through technology instructions. Further, it elucidates the technological impacts in the distance learning scenario. Consequently, it argues that the intervention of suitable and advanced technology helps learners to develop their cognitive skills and assists in their learning activities.
Numerical Verification of Industrial Numerical Codes
Denis Christophe,Montan Sethy
ESAIM : Proceedings , 2012, DOI: 10.1051/proc/201235006
Abstract: Several approximations occur during a numerical simulation: physical effects mapy be discarded, continuous functions replaced by discretized ones and real numbers replaced by finite-precision representations. The use of the floating point arithmetic generates round-off errors at each arithmetical expression and some mathematical properties are lost. The aim of the numerical verification activity at EDF R&D is to study the effect of the round-off error propagation on the results of a numerical simulation. It is indeed crucial to perform a numerical verification of industrial codes such as developped at EDF R&D even more for code running in HPC environments. This paper presents some recent studies around the numerical verification at EDF R&D. Le résultat d’un code de simulation numérique subit plusieurs approximations effectuées lors de la modélisation mathématique du problème physique, de la discrétisation du modèle mathématique et de la résolution numérique en arithmétique flottante. L’utilisation de l’arithmétique flottante génère en effet des erreurs d’arrondi lors de chaque opération flottante et des propriétés mathématiques sont perdues. Il existe à EDF R&D une activité transverse de vérification numérique consistant à étudier l’effet de la propagation des erreurs d’arrondi sur les résultats des simulations. Il est en effet important de vérifier numériquement des codes industriels et ce d’autant plus s’ils sont éxécutés dans environnements de calcul haute performance. Ce papier présente des études récentes autour de la vérification numérique à EDF R&D.
Benefits of Simple Exchange Transfusion in Sickle Cell Disease (HbSS) with Vaso-Occlusive Crisis Not Responding to Standard Therapy  [PDF]
Dibyajyoti Sahoo, Rabindra Kumar Jena, Sudha Sethy, Sambit Kumar Behera
International Journal of Clinical Medicine (IJCM) , 2016, DOI: 10.4236/ijcm.2016.71010
Abstract: Sickle cell disease is an autosomal recessive genetic disease. Vaso occlusive crisis (VOC) is frequently seen in such patients. Painful VOC is usually recurrent, of variable severity due to many factors and its management poses important challenge in the clinical practice. Few patients do not respond to standard therapies and continue to suffer severe pain for prolonged period or land to serious life threatening situation. The red cell exchange by aphaeresis is presumed to be one efficient alternative in this situation which can reduce the level of HbS below 40% - 50%. However, it is costly and not available everywhere. Both circumstances are common in our state where incidence of sickle cell disease is quite high. In such situations simple red cell exchange i.e. removing 1 unit (350 ml) of blood manually (by phlebotomy) and replacement with one unit normal red cell is effective. All of our four cases of SCA with severe acute VOC, are not responding to standard therapy but responded efficiently to this simple red cell exchange transfusion. Our present observation may pave the way of one simple, affordable, and effective measure to reduce the pain of severe acute VOC not responding to standard therapy. Moderate reduction of HbS by 8% - 14% by simple red cell exchange transfusion was associated with relief of pain of acute VOC; a new observation was reported in all our 4 cases which need to be validated by larger controlled studies.
LOW LEVEL OBJECT ORIENTED LANGUAGE IN CONTEXT OF COMPARATIVE STUDY BETWEEN TWO LOW LEVEL LANGUAGES MSIL(MICROSOFT INTERMEDIATE LANGUAGE)OR CIL AND JAVA BYTE CODE
Amit Juyal,Ashish Pal,Janmejay Pant
International Journal of Engineering Science and Technology , 2012,
Abstract: Most of the software were developed using high level languages such as Java, C#.NET,VB.NET etc. The main advantages of these languages are object oriented features .Which helps to developer to develop software with graphical user interface, portable, ease of use ,efficient and secure .Low level language like assembly language,machine languages are not user friendly ,hard to program but faster in execution than high level languages..In this paper we have done comparative study between two low level language MSIL(Micro Soft Intermediate language)or CIL and Java Byte Code. Both of these languages have object oriented features. This paper also includes brief introduction about programming languages, and translators.
Research: VALIDATED HPTLC METHOD FOR SIMULTANEOUS QUANTITATION OF CEFIXIME AND OFLOXACIN IN BULK DRUG AND IN PHARMACEUTICAL FORMULATION
Janhavi Rao*,Kamini Sethy,Savita Yadav
Pharmacie Globale : International Journal of Comprehensive Pharmacy , 2011,
Abstract: This work is concerned with the simultaneous determination of cefixime and ofloxacin in a bulk drug and pharmaceutical formulations by high performance thin layer chromatographic (HPTLC) method. Chromatographic separation was achieved on aluminum foil plates precoated with silica gel 60GF-254, with n-butanol: ammonia: water: DMSO (8:3:1:2, v/v/v/v) as mobile phase. Detection was performed densitometrically at 297 nm. The RF of cefixime and ofloxacin were 0.55 and 0.65, respectively. The reliability of the method was assessed by evaluation of linearity (30-180 ng/spot for both cefixime and ofloxacin respectively. Accuracy (99.82 % for cefixime and 99.84 % for ofloxacin), and specificity, in accordance with ICH guidelines. The method is simple, accurate, and rapid and can therefore be used for routine analysis of both drugs in quality control laboratories.
Randomized open comparative trial of dexamethasone-cyclophosphamide pulse and daily oral cyclophosphamide versus cyclophosphamide pulse and daily oral prednisolone in pemphigus vulgaris
Sethy Pradeep,Khandpur Sujay,Sharma Vinod
Indian Journal of Dermatology, Venereology and Leprology , 2009,
Abstract: Background: In various case series, pulse therapy has shown good results in pemphigus vulgaris (PV), with long-term remissions. Aims: To compare the efficacy and side-effects of dexamethasone-cyclophosphamide pulse and daily oral cyclophosphamide (DCP+C) versus cyclophosphamide pulse and daily oral prednisolone (CP+P) in PV. Methods: Twenty-eight active PV patients were randomized to receive either DCP with daily oral cyclophosphamide (Group A, n = 15) or CP with tapering doses of daily oral prednisolone (Group B, n = 13) for 12 months and followed-up for at least 3 months after stopping therapy. They were compared for time taken to achieve mucocutaneous disease control, achieve remission, relapse during treatment period, relapse after stopping therapy and side-effects. Results: Of 28 cases, 25 (Group A - 15, Group B - 10) completed the study period and were analyzed. The time for initiation of cutaneous response and time to achieve complete disease remission were significantly lesser in group B. However, other efficacy parameters were comparable. In Group A, significant adverse events were dysgusea, hiccups, palpitation, nail discoloration, bone pain and urinary tract infection while in Group B, they included nausea, moon facies, flushing, secondary amenorrhea, steroid withdrawal symptoms and dyspnea due to weight gain. Conclusions: Early remission was achieved in group B but the relapse rates during the treatment phase or after stopping therapy were comparable. Both therapies had comparable side-effect profiles, although Group B showed greater steroid-induced adverse events.
RADIOPHARMACEUTICALS FOR IMAGING OF HYPOXIC TUMORS: A REVIEW
Chaitanya Prasad Meher,Sarada Prasanna Sethy
International Research Journal of Pharmacy , 2012,
Abstract: Radiopharmaceuticals are drugs containing a radionuclide and are used routinely in nuclear medicine for the diagnosis and therapy of various diseases. The mechanism of localization of the radiopharmaceutical in different organs provides the clue for designing of the agent meant for a specific organ or pathway. Various agent like F-18, Cu-64/67, I-123, and Tc-99m are used as imaging of hypoxic tumors. Of these, F-18-fluoromisonidazole and I-123-iodoazomycin arabinoside (IAZA) have been most widely studied clinically. Non-nitro-containing bioreductive complexes, such as the Cu-60/62/64 thiosemicarbazone ATSM and Tc-99m butylene amineoxime (BnAO or HL91), have also been evaluated. In particular, I-123-IAZA and Cu-60-ATSM have shown correlation with response to radiotherapy in preliminary clinical studies. However, more preclinical studies comparing imaging with validated invasive methods and clinical studies with outcome measures are required. Nuclear medicine is poised to play an important role in optimizing the therapy of patients with hypoxic tumors. The present review is concern with the various radiopharmaceuticals used for imaging of hypoxia.
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