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The milk quality and feasebility analysis of loose housing dairy cows - a case study
Marjan Jan?ekovi?,?rtomir Rozman
Mljekarstvo , 2006,
Abstract: The aim of the study was technological and economical analysis of free range cow breeding. The case study analyzed two different systems of holstein-friesian dairy cows breeding. The model total costs enterprise budget was developed for evaluation of economic feasibility of loose housing dairy cows in comparison with tied cow breeding system. Computer supported calculation enabled estimation of the most important economical parameters (net return, total cost, and coefficient of economics). Results obtained show that (at observed input parameters) loose housing system is economically feasible, if there is a minimum of 41 dairy cows with an average milk production of 8610 kg per cow. It was also established that cows need approximately 6 months to fully adapt to the loose housing system.
The glove thrown down - responses
Darija Rozman
Knji?nica : Revija za Podro?je Bibliotekarstva in Informacijske Znanosti , 2008,
Abstract:
Reflexiones sobre la universidad en el ámbito biomédico Reflections on the University from a Biomedical Perspective
Ciril Rozman
Educación Médica , 2005,
Abstract:
Financial evaluation of competitive ability of fruit growing in Bosnia and Herzegovina
?ejvanovi? Ferhat,Rozman ?rtomir
Economic Annals , 2004, DOI: 10.2298/eka0461193c
Abstract: Before making a decision to invest in fruit growing, an investor needs to have the basic information on which to base his decision. This information contains sufficient economic indicators to form the basis for the decision making. The decision should be based, first of all, on economic profitability of the investment. Cost-benefit analysis is a method which provides the decision maker with the information about a number of economic indicators regarding the desired investment, from its profitability and competitiveness to the return on investment period, etc. This paper deals with the cost-benefit analysis in the decision-making process concerning economic profitability of investing in agricultural production, namely the newly planted fruit. Cost-benefit analysis has many advantages compared with the other known methods. It has proved very useful in agricultural production since it makes it possible to estimate the profitability of investment in very specific conditions of agricultural production, taking into account numerous factors of its economic efficiency as well as the main effects that may be expected both by individual producers and the social community as a whole.
Recognition of Transient Phenomena in a Biosignal
K. Marsalek,J. Rozman
Radioengineering , 2000,
Abstract: Electrical Activity of a human brain measured on the skull(electroencephalogram, EEG) contains in the sleep period manytransients (sleep spindles, spike-like structures or vertex waves), i.e. bursts of EEG activity of limited duration, having random occurrenceand may be coupled with specific sleep stages. A computer-baseddetector was designed that detects a transient called K-complex. Thedetector is based on linear matched filtering and its nonlinearmodifications. The linear and nonlinear approaches are compared andevaluated with respect to the detection efficiency.
Comparison of particle-exposure triggered pulmonary and systemic inflammation in mice fed with three different diets
Alexander A G?tz, Jan Rozman, Heiko G R?del, Helmut Fuchs, Valérie Gailus-Durner, Martin Hrabě de Angelis, Martin Klingenspor, Tobias Stoeger
Particle and Fibre Toxicology , 2011, DOI: 10.1186/1743-8977-8-30
Abstract: In this study we addressed the question, whether a diet challenge increases the inflammatory response in the alveolar and the blood compartment in response to carbon nanoparticles (CNP), as a surrogate for ambient/urban particulate air pollutants.Mice were fed a high caloric carbohydrate-rich (CA) or a fat-rich (HF) diet for six weeks and were compared to mice kept on a purified low fat (LF) diet, respectively. Bronchoalveolar lavage (BAL) and blood samples were taken 24 h after intratracheal CNP instillation and checked for cellular and molecular markers of inflammation.The high caloric diets resulted in distinct effects when compared with LF mice, respectively: CA resulted in increased body and fat mass without affecting blood cellular immunity. Conversely, HF activated the blood system, increasing lymphocyte and neutrophil counts, and resulted in slightly increased body fat content. In contrast to higher pro-inflammatory BAL Leptin in CA and HF mice, on a cellular level, both diets did not lead to an increased pro-inflammatory basal status in the alveolar compartment per se, nor did result in differences in the particle-triggered response. However both diets resulted in a disturbance of the alveolar capillary barrier as indicated by enhanced BAL protein and lactate-dehydrogenase concentrations. Systemically, reduced serum Adiponectin in HF mice might be related to the observed white blood cell increase.The increase in BAL pro-inflammatory factors in high caloric groups and reductions in serum concentrations of anti-inflammatory factors in HF mice, clearly show diet-specific effects, pointing towards augmented systemic inflammatory conditions. Our data suggest that extended feeding periods, leading to manifest obesity, are necessary to generate an increased susceptibility to particle-induced lung inflammation; although the diet-challenge already was efficient in driving pro-inflammatory systemic events.Obesity and its common sequelae (e.g. type II diabetes and car
Blood and Synovial Microparticles as Revealed by Atomic Force and Scanning Electron Microscope
Ita Junkar, Vid u tar, Mojca Frank, Vid Jan a, Apolonija Bedina Zavec, Blaz Rozman, Miran Mozetic, Henry HagerstrandVeronika Kralj-Iglic
The Open Autoimmunity Journal , 2009, DOI: 10.2174/1876894600901010050]
Abstract: Microvesicles which are pinched off the cell membrane can be considered extracellular organelles which mediate interaction between distal cells. They were suggested to play an important role in many diseases including autoimmune disorders, however, standard methods for their assessment have not yet been decided upon while their clinical relevance and the underlying mechanisms are yet unclear. We present a pilot study results involving atomic force microscope (AFM) and scanning electron microscope (SEM) images of the material isolated from peripheral blood of healthy donors and from synovial fluid of patients with psoriatic arthritis and rheumatoid arthritis, which is expected to contain microvesicles. Micrographs reveal in the samples isolated from blood the presence of globular and tubular structures which are most probably microvesicles while the identity of grain-like structures isolated from synovial fluid remains obscure. To the best of our knowledge the AFM and SEM images of the material isolated from synovial fluid are presented for the first time.
Resistência do Mycobacterium tuberculosis às drogas em pacientes HIV+ em cinco municípios da Baixada Santista, S?o Paulo, Brasil
Rozman, Luciana Martins;Santo, Augusto Hasiak;Rozman, Mauro Abrah?o;
Cadernos de Saúde Pública , 2007, DOI: 10.1590/S0102-311X2007000500007
Abstract: since the early 1990s, an increase in mycobacterium tuberculosis drug resistance has been reported, with high prevalence among hiv+ patients. we evaluated the sensitivity patterns of m. tuberculosis, resistance rate, and predisposing factors among hiv+ patients in santos, s?o vicente, cubat?o, praia grande, and guarujá, s?o paulo state, brazil. the medical charts of 301 patients with positive cultures for m. tuberculosis from 1993 to 2003 were reviewed. resistance occurred in 57 patients (18.9%), as follows: 32 (10.6%) displayed multidrug-resistant tuberculosis (resistant to at least rifampicin and isoniazid); 4 (1.3%) were resistant to two or more drugs; and 21 (7%) were resistant to a single drug. acquired resistance was observed in 70.1% of cases. drug resistance was significantly associated with previous tuberculosis treatment, duration of hiv diagnosis, and previous hospitalization. in logistic regression analysis, only previous tuberculosis treatment adjusted by age remained as an independent risk factor (or = 5.49; 95%ci: 2.60-11.60). drug resistance to at least one drug in 18.9% and multidrug resistance in 10.6% of cases highlight the relevance of this problem in hiv patients in the baixada santista.
Nonalcoholic Fatty Liver Disease: Focus on Lipoprotein and Lipid Deregulation
Klementina Fon Tacer,Damjana Rozman
Journal of Lipids , 2011, DOI: 10.1155/2011/783976
Abstract: Obesity with associated comorbidities is currently a worldwide epidemic and among the most challenging health conditions in the 21st century. A major metabolic consequence of obesity is insulin resistance which underlies the pathogenesis of the metabolic syndrome. Nonalcoholic fatty liver disease (NAFLD) is the hepatic manifestation of obesity and metabolic syndrome. It comprises a disease spectrum ranging from simple steatosis (fatty liver), through nonalcoholic steatohepatitis (NASH) to fibrosis, and ultimately liver cirrhosis. Abnormality in lipid and lipoprotein metabolism accompanied by chronic inflammation is the central pathway for the development of metabolic syndrome-related diseases, such as atherosclerosis, cardiovascular disease (CVD), and NAFLD. This paper focuses on pathogenic aspect of lipid and lipoprotein metabolism in NAFLD and the relevant mouse models of this complex multifactorial disease. 1. Introduction Nonalcoholic fatty liver disease (NAFLD) is progressively diagnosed worldwide and is considered to be the most common liver disorder in Western countries, estimated to affect at least one-quarter of the general population [1, 2]. NAFLD used to be almost exclusively a disease of adults but is now becoming a significant health issue also in obese children. The prevalence of childhood obesity has significantly increased over the past three decades [3, 4] and boosted the prevalence of NAFLD in adolescents (reviewed in [5]). NAFLD covers a spectrum of hepatic pathologies, ranging from simple steatosis to nonalcoholic steatohepatitis (NASH). It strongly associates with obesity, insulin resistance, hypertension, and dyslipidaemia and is now regarded as the liver manifestation of metabolic syndrome [6]. Simple steatosis is largely benign and nonprogressive whereas NASH is characterized by hepatocyte injury, inflammation, and fibrosis and can lead to cirrhosis, liver failure, and hepatocellular carcinoma [7]. Lipid accumulation in the liver is the major hallmark of NAFLD. A comprehensive understanding of the mechanisms leading to liver steatosis and further transition to nonalcoholic steatohepatitis (NASH) still remains elusive. There is no simple solution to understand the multi-factorial nature of NAFLD appearance and progression, presumably due to the nonlinear interactions of those factors. Abnormalities in lipid and lipoprotein metabolism accompanied by chronic inflammation are considered to be the central pathway for the development of several obesity-related co-morbidities such as NAFLD and cardio-vascular disease (CVD) [8, 9]. NAFLD
Quality of life following thoracotomy for lung cancer
Lu ka Debevec, Irma Rozman
Radiology and Oncology , 2007, DOI: 10.2478/v10019-007-0023-8
Abstract: Background. The aim of the study was to assess the preoperative and postoperative quality of life (QoL) in lung cancer patients undergoing thoracotomy and to compare the impairment of QoL in resected and exploratory thoracotomized (ET) patients. Patients and methods. Forty-three patients age 31 to 82 (mean 61) thoracotomized (lobectomy 29, bilobectomy 1, pneumonectomy 8, ET 5) for non-small cell lung cancer were assessed using the EORTC QLQ-LC30 and QLQ-LC13 questionnaire preoperatively and a mean of 45±17 days after the thoracotomy and before eventual chemotherapy and radiation therapy. Results. After thoracotomy there were significantly impaired functional scales (physical functioning, role functioning, social functioning) and symptom scales (fatigue, constipation, appetite loss, dyspnoea, pain). The remaining symptoms (nausea/vomiting, insomnia, diarrhoea, coughing), global health status, functional scales (emotional functioning, cognitive functioning) and financial difficulties were impaired non-significantly. However, haemoptysis significantly improved and completely disappeared after thoracotomy. There were no significant differences between resected and ET patients. Conclusions. The study established significant impairment of QoL in the first two months after thoracotomy, but no significant differences between resected and ET patients.
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