2015 ( 50 )

2014 ( 55 )

2013 ( 64 )

2012 ( 83 )


匹配条件: “ Frauke Neff” ,找到相关结果约492条。
Gastarbeiterinnen in der Bundesrepublik Female Guest Workers in Germany
Frauke Miera
querelles-net , 2007,
Abstract: Monika Mattes untersucht in ihrem Buch erstmals umfassend und detailliert die Geschichte der Anwerbung ausl ndischer Frauen in der Bundesrepublik der 1950er bis 1970er Jahre. Indem sie die Kategorie Geschlecht systematisch in ihre Analyse einbezieht, vermag sie gel ufige Periodisierungen und Konzepte der bisher weitgehend geschlechtsblinden Forschung zum Thema Gastarbeit“ zu hinterfragen und teilweise neu zu formulieren. Darüber hinaus betrachtet die Autorin die strukturellen und diskursiven Verknüpfungen von Frauenerwerbsarbeit und Ausl nderbesch ftigung und verbindet auf diese Weise historische Migrations- und Geschlechterforschung. For the first time, Monika Mattes’ book presents a comprehensive and detailed examination of the history of the recruitment of foreign women workers in Germany from the 1950s to the 1970s. Through her systematic inclusion of the category of gender, Mattes questions and partially reformulates current research on the theme of “guest work,” which, till now, has been for the most part gender-blind. Moreover, the author examines the structural and discursive connections between the gainful employment of women and the employment of foreigners, thus conjoining historical migration and gender research.
Die Soldatenmütter Sankt Petersburg The Soldiers’ Mothers of St. Petersburg
Frauke Wetzel
querelles-net , 2001,
Abstract: Eine wachsende Zahl von Frauen in Ru land schafft es, gegen die tragende Rolle des Milit rs zu rebellieren. Sie leisten Widerstand gegen die undemokratischen Streitkr fte, in denen Wehrdienstleistende mi handelt und gefoltert werden. Eva Maria Hinterhuber, selbst für einige Zeit Mitarbeiterin der Soldatenmütter Sankt Petersburg, schreibt in ihrer nun ver ffentlichten Diplomarbeit über eine Gruppe von Widerst ndigen, ihre Rolle im Transformationsproze und ihre Bedeutung für das Entstehen einer Zivilgesellschaft in Ru land. An increasing number of women is successfully rebelling against the Russian army. They try to resist an undemocratic military force where soldiers are ill-treated and tortured. Eva Maria Hinterhuber, a former employee at the St. Peterburg Soldiers’ Mothers, writes in her recently published thesis about one group of opposers, their role in the process of transformation and their importance for the development of a civil society in Russia.
Vers le Sud : le voyage de Johann Georg von Dillis à travers la France, la Suisse et l'Italie en 1806
Josenhans, Frauke
RIHA Journal , 2011,
Abstract: Southern France, and Provence in particular, started to lure painters as early as in the 18th century, first and foremost French ones, and then increasingly foreign painters, notably the German landscapist Johann Georg von Dillis. In 1806, he undertook a journey in the South of France in the company of the Bavarian crown prince, the future Ludwig I. Dillis' journey is known from two different sources: a group of drawings known as the Voyage pittoresque dans le Midi de la France dessiné par Dillis (Staatliche Graphische Sammlung, Munich) and his unpublished correspondence with his brother Ignaz Dillis. The drawings, which were ordered by the prince as a visual souvenir of his tour, reflect Ludwig's interest in Roman Antiquity and thus include numerous views of ancient monuments, such as the Maison Carrée in N mes, the arc de triomphe in Orange and the ruins in Saint-Rémy-de-Provence. Apart from this group there is another body of drawings, which Dillis also made during the journey, but that he chose not to include in the Voyage pittoresque. These sheets attest to the draughtsman's attentiveness and sensibility for nature more obviously than the commissioned drawings. An official commission, the Voyage pittoresque is an exceptional artistic testimony of travel in the early 19th century. It shows that Provence became attractive for artists earlier than was previously thought.
Mapping the Past: Eduard Paulus the Elder (1803–1878) and the Archaeological Survey of Wu rttemberg
Frauke Kreienbrink
Bulletin of the History of Archaeology , 2007, DOI: 10.5334/bha.17202
Abstract: In 1858 Karl Eduard Paulus caused a minor sensation at the annual meeting of the General Association of German Antiquarian Societies (Gesamtverein deutscher Geschichts- und Alterthumsvereine, from now on referred to simply as the General Association) by presenting his archaeological map of the Kingdom of Wu rttemberg, in south-western Germany. It was the first detailed map of an entire German state to record archaeological monuments. Systematic archaeological surveys and mapping of monuments and finds had occasionally been produced by scholars from the early nineteenth century, and some archaeological maps already existed for some regions; but Paulus’ map, published in 1859, was exceptional. In this paper I will point out what was so new about this map. Moreover I will examine how the antiquarian research of Paulus in general, and his archaeological map in particular, were integrated into his extensive concept of the natural and cultural landscape. And I will discuss whether there were special conditions in Wu rttemberg that promoted such enterprises – or whether this enterprise was the consequence of the private initiative of an individual.
Networks, Contacts and Competition in the History of Archaeology – A One Day Research Meeting, Held on Saturday, 15 July 2006 at Durham University
Frauke Kreienbrink
Bulletin of the History of Archaeology , 2006, DOI: 10.5334/bha.16208
Finding Starting-Values for the Estimation of Vector STAR Models
Frauke Schleer
Econometrics , 2015, DOI: 10.3390/econometrics3010065
Abstract: This paper focuses on finding starting-values for the estimation of Vector STAR models. Based on a Monte Carlo study, different procedures are evaluated. Their performance is assessed with respect to model fit and computational effort. I employ (i) grid search algorithms and (ii) heuristic optimization procedures, namely differential evolution, threshold accepting, and simulated annealing. In the equation-by-equation starting-value search approach the procedures achieve equally good results. Unless the errors are cross-correlated, equation-by-equation search followed by a derivative-based algorithm can handle such an optimization problem sufficiently well. This result holds also for higher-dimensional Vector STAR models with a slight edge for heuristic methods. For more complex Vector STAR models which require a multivariate search approach, simulated annealing and differential evolution outperform threshold accepting and the grid search.
Universal deformation rings and dihedral 2-groups
Frauke Bleher
Mathematics , 2007, DOI: 10.1112/jlms/jdn071
Abstract: Let $k$ be an algebraically closed field of characteristic 2, and let $W$ be the ring of infinite Witt vectors over $k$. Suppose $D$ is a dihedral 2-group. We prove that the universal deformation ring $R(D,V)$ of an endo-trivial $kD$-module $V$ is always isomorphic to $W[\mathbb{Z}/2\times\mathbb{Z}/2]$. As a consequence we obtain a similar result for modules $V$ with stable endomorphism ring $k$ belonging to an arbitrary nilpotent block with defect group $D$. This confirms for such $V$ conjectures on the ring structure of the universal deformation ring of $V$ which had previously been shown for $V$ belonging to cyclic blocks or to blocks with Klein four defect groups.
Small-Animal PET Imaging of Amyloid-Beta Plaques with [11C]PiB and Its Multi-Modal Validation in an APP/PS1 Mouse Model of Alzheimer's Disease
André Manook, Behrooz H. Yousefi, Antje Willuweit, Stefan Platzer, Sybille Reder, Andreas Voss, Marc Huisman, Markus Settles, Frauke Neff, Joachim Velden, Michael Schoor, Heinz von der Kammer, Hans-Jürgen Wester, Markus Schwaiger, Gjermund Henriksen, Alexander Drzezga
PLOS ONE , 2012, DOI: 10.1371/journal.pone.0031310
Abstract: In vivo imaging and quantification of amyloid-β plaque (Aβ) burden in small-animal models of Alzheimer's disease (AD) is a valuable tool for translational research such as developing specific imaging markers and monitoring new therapy approaches. Methodological constraints such as image resolution of positron emission tomography (PET) and lack of suitable AD models have limited the feasibility of PET in mice. In this study, we evaluated a feasible protocol for PET imaging of Aβ in mouse brain with [11C]PiB and specific activities commonly used in human studies. In vivo mouse brain MRI for anatomical reference was acquired with a clinical 1.5 T system. A recently characterized APP/PS1 mouse was employed to measure Aβ at different disease stages in homozygous and hemizygous animals. We performed multi-modal cross-validations for the PET results with ex vivo and in vitro methodologies, including regional brain biodistribution, multi-label digital autoradiography, protein quantification with ELISA, fluorescence microscopy, semi-automated histological quantification and radioligand binding assays. Specific [11C]PiB uptake in individual brain regions with Aβ deposition was demonstrated and validated in all animals of the study cohort including homozygous AD animals as young as nine months. Corresponding to the extent of Aβ pathology, old homozygous AD animals (21 months) showed the highest uptake followed by old hemizygous (23 months) and young homozygous mice (9 months). In all AD age groups the cerebellum was shown to be suitable as an intracerebral reference region. PET results were cross-validated and consistent with all applied ex vivo and in vitro methodologies. The results confirm that the experimental setup for non-invasive [11C]PiB imaging of Aβ in the APP/PS1 mice provides a feasible, reproducible and robust protocol for small-animal Aβ imaging. It allows longitudinal imaging studies with follow-up periods of approximately one and a half years and provides a foundation for translational Alzheimer neuroimaging in transgenic mice.
Multimodality Multiparametric Imaging of Early Tumor Response to a Novel Antiangiogenic Therapy Based on Anticalins
Reinhard Meier, Rickmer Braren, Yvonne Kosanke, Johanna Bussemer, Frauke Neff, Moritz Wildgruber, Sarah Schwarzenb?ck, Annette Frank, Bernhard Haller, Andreas M. Hohlbaum, Markus Schwaiger, Hendrik Gille, Ernst J. Rummeny, Ambros J. Beer
PLOS ONE , 2014, DOI: 10.1371/journal.pone.0094972
Abstract: Anticalins are a novel class of targeted protein therapeutics. The PEGylated Anticalin Angiocal (PRS-050-PEG40) is directed against VEGF-A. The purpose of our study was to compare the performance of diffusion weighted imaging (DWI), dynamic contrast enhanced magnetic resonance imaging (DCE)-MRI and positron emission tomography with the tracer [18F]fluorodeoxyglucose (FDG-PET) for monitoring early response to antiangiogenic therapy with PRS-050-PEG40. 31 mice were implanted subcutaneously with A673 rhabdomyosarcoma xenografts and underwent DWI, DCE-MRI and FDG-PET before and 2 days after i.p. injection of PRS-050-PEG40 (n = 13), Avastin (n = 6) or PBS (n = 12). Tumor size was measured manually with a caliper. Imaging results were correlated with histopathology. In the results, the tumor size was not significantly different in the treatment groups when compared to the control group on day 2 after therapy onset (P = 0.09). In contrast the imaging modalities DWI, DCE-MRI and FDG-PET showed significant differences between the therapeutic compared to the control group as early as 2 days after therapy onset (P<0.001). There was a strong correlation of the early changes in DWI, DCE-MRI and FDG-PET at day 2 after therapy onset and the change in tumor size at the end of therapy (r = ?0.58, 0.71 and 0.67 respectively). The imaging results were confirmed by histopathology, showing early necrosis and necroptosis in the tumors. Thus multimodality multiparametric imaging was able to predict therapeutic success of PRS-050-PEG40 and Avastin as early as 2 days after onset of therapy and thus promising for monitoring early response of antiangiogenic therapy.
Computational Fluid Dynamics and Its Impact on Flow Measurements Using Phase-Contrast MR-Angiography  [PDF]
Claus Kiefer, Frauke Kellner-Weldon
Open Journal of Medical Imaging (OJMI) , 2012, DOI: 10.4236/ojmi.2012.21004
Abstract: Rationale and Objectives: Computational fluid dynamic (CFD) simulations are discussed with respect to their potential for quality assurance of flow quantification using commercial software for the evaluation of magnetic resonance phase contrast angiography (PCA) data. Materials and Methods: Magnetic resonance phase contrast angiography data was evaluated with the Nova software. CFD simulations were performed on that part of the vessel system where the flow behavior was unexpected or non-reliable. The CFD simulations were performed with in-house written software. Results: The numerical CFD calculations demonstrated that under reasonable boundary conditions, defined by the PCA velocity values, the flow behavior within the critical parts of the vessel system can be correctly reproduced. Conclusion: CFD simulations are an important extension to commercial flow quantification tools with regard to quality assurance.

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